The toxicology lab examines the response of Tetrahymena cells to a variety of basic substances, looking at both acute lethal toxicity (LD50) and chronic sub-lethal toxicity. Students can use different concentrations of common substances suggested in the module (for example, shampoo, detergents, toothpaste, Windex) to determine lethal and sub-lethal dosage, or, under teacher supervision, design their own experiment to look at common substances of interest to them. The lab offers an opportunity for students at all levels to begin to address experimental design, the effect of experimental variables, and potential long term environmental impact of even commonly used items.

Module Protocols

High School

Relevant Concepts

Science, Technology, and Society; Environmental Impact on Growth and Survival; Ecosystems and Relationships between Organisms

Next Generation Science Standards Relationships

High School: HS-LS2-1 | HS-LS2-7 | HS-LS3-2 | HS-LS4-5 | HS-LS4-6 | HS-ESS3-4

Middle School: MS-LS1-1 | MS-LS1-2 | MS-LS1-5 | MS-LS2-4 | MS-LS4-4

NYS Science Curriculum Guideline Relationships

Key Ideas 1.1 | 1.2 | 1.3 | 4.5 | 4.6 | 4.7